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Acne – Why you get it?

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Acne this unsightly condition is feared by every teenager. A mild case can be unpleasant a severe case can cause lifelong disfigurement . Acne is an inflammatory disease of the skin, caused by changes in the pilosebaceous units (skin structures consisting of a hair follicle and its associated sebaceous gland). Having Severe Acne May Increase Suicide Risk, Study Suggests – Individuals who suffer from severe acne are at an increased risk of attempting suicide, a new study … So it is important to try to at the very least control the outbreaks. First of all you must keep your skin clean by washing with ‘Skin detergent’. Acne Really Is A Nightmare For Some Teens — Zits, pimples, bumps and blemishes are a young person’s worst nightmare. Collectively they are known as acne, a very common skin condition that affects millions of adolescents.

A New Study Claims Acne Is Not Associated With Yet-Uncultured Bacteria — researchers from Aarhus University, Denmark found bacteria in the follicles of acne patients and healthy individuals to be those of previously known species, disputing the theory… The largest study ever conducted on acne and stress reveals that teenagers who were under high levels of stress were 23 percent more likely to have increased acne severity, according to researchers from Wake Forest University School of Medicine and colleagues. “Acne significantly affects physical and psychosocial well-being, so it is important to understand the interplay between the factors that exacerbate acne,” said Gil Yosipovitch, M.D., lead author and a professor of dermatology. “Our study suggests a significant association between stress and seventy of acne.” The results of the study, which involved 94 adolescents from Singapore, are reported today in Acts Derm Venereol, a Swedish medical journal.

While psychological stress had been identified among many factors that can women acne, there has been little research to understand the mechanisms behind this relationship. The current study looked at whether levels of sebum, the oily substance that coats the skin and protects the hair, increase in times of stress and are related to acne severity. Hormone levels, sebum production and bacteria are all known to play major roles in acne. The study involved secondary school students in Singapore with a mean age of 14.9 years. The students’ self-reported stress levels and acne severity were measured at two different times — just before mid-year exams and during summer break. Students’ long-term career prospects are influenced by the results of the examinations and they are known to induce psychological stress. Stress levels were measured using the Perceived Stress Scale, a 14-item, self-questionnaire that is widely used in stress research. Acne severity was measured using a system that classifies acne based on type and number of lesions. Ninety-two percent of the girls and 95 percent of the boys reported having acne.

Since acne is an inflammatory disease of the skin caused by changes in the hair follicle and the sebaceous glands of the skin that produce sebum. The oily substance plugs the pores it just makes since to clean your oily face with Skin detergent. The teenage years are stressful but you must relax because researchers suspect that stress increases the quantity of sebum, which leads to increased acne. Researchers found that students reporting high stress were 23 percent more likely to have increased severity of acne suggests that acne severity associated with stress may play a key role . Singapore was selected as the study location because sebum production is known to fluctuate with variations in temperature and humidity. In Singapore’s tropical climate, temperature and humidity are consistent throughout the year.

The bacteria that cause acne live on everyone’s skin, yet one in five people is lucky enough to develop only an occasional pimple over a lifetime. What’s their secret? In a break through for teenagers everywhere, a UCLA study conducted with researchers at Washington University in St. Louis and the Los Angeles Biomedical Research Institute has discovered that acne bacteria contain “bad” strains associated with pimples and “good” strains that may protect the skin. The findings, published in the Feb. 28 edition of the Journal of Investigative Dermatology, could lead to a myriad of new therapies to prevent and treat the disfiguring skin disorder. “We learned that not all acne bacteria trigger pimples — one strain may actually help keep skin healthy,” said lead author Huia Li, an assistant professor of molecular and medical pharmacology at the David Geffen School of Medicine at UCLA. “We hope to apply our findings to develop new strategies that stop blemishes before they start, and enable dermatologists to customize treatment to each patient’s unique cocktail of skin bacteria.

The scientists looked at a tiny microbe with a big name: Propionibacterium acnes, bacteria that thrive in the oily depths of our pores. When the bacteria aggravate the immune system, they cause the swollen, red bumps associated with acne. Using over-the-counter pore-cleansing strips, LA BioMed and UCLA researchers lifted P. acnes bacteria from the noses of 49 pimply and 52 clear-skinned volunteers. After extracting the microbial DNA from the strips, Li’s laboratory tracked a genetic marker to identity the bacterial strains in each volunteer’s pores and recorded whether the person suffered from acne.

Next, Li’s lab cultured the bacteria from the strips to isolate more than 1,000 strains. Washington University scientists sequenced the genomes of 66 of the P. acnes strains, enabling UCLA co-first author Shuta Tomida to zero in on genes unique to each strain. “We were interested to learn that the bacterial strains looked very different when taken from diseased skin, compared to healthy skin,” said co-author Dr. Noah Craft, a dermatologist and director of the Center for Immunotherapeutics Research at LA BioMed at Harbor-UCLA Medical Center. “Two unique strains of P. acnes appeared in one out of five volunteers with acne but rarely occurred in clear-skinned people.” The biggest discovery was still to come. “We were extremely excited to uncover a third strain of P acnes that’s common in healthy skin yet rarely found when acne is present,” said Li, who is also a member of UCLA’s Crump Institute for Molecular Imaging. “We suspect that this strain contains a natural defense mechanism that enables it to recognize attackers and destroy them before they infect the bacterial cell.” No matter what you still must keep your skin clean with ‘skin detergent or a similar product. The researchers believe that increasing the body’s friendly strain of bacteria may offer new hope to those with acne.
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